Pharmaceutical intermediates:
1. Core raw materials for synthesizing anti tuberculosis drugs (such as pyrazinamide, pyrazinamide, CAS 98-96-4)
2. Used for constructing heterocyclic drugs (such as anti-tumor and antiviral compounds)

Ligands and catalysts:
1. As a metal ligand (such as ruthenium, copper complexes) for homogeneous catalytic reactions

Food and spices:
1. Pyrazine derivatives are food aroma enhancers (such as baking and nutty flavors)