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Ethyl 4-piperidinecarboxylate

Product name Ethyl 4-piperidinecarboxylate,
Ethyl piperidine-4-carboxylate,
Ethyl 4-piperidinecarboxylate
CAS No. 1126-09-6
Molecular formula C8H15NO2
Use

Drug intermediates:
1. Used for synthesizing local anesthetics (such as structural fragments of piperidine derivative ropivacaine).
2. Construct a pyridine ring skeleton for analgesics (such as opioid receptor modulators) and antipsychotic drugs.
3. Participate in the preparation of anticholinergic drugs (such as drugs for treating Parkinson's disease or gastrointestinal spasms).

Ester reactivity:
1. It can be hydrolyzed to generate 4-piperidinecarboxylic acid (CAS 498-94-2), or reduced to piperidomethanol.
2. Used for amidation reactions (such as condensation with amines to prepare piperidinecarboxamide derivatives).
3. Chiral synthesis: used as a precursor for chiral pyridine rings in asymmetric catalytic reactions.

Pesticides and functional materials:
1. Pesticide intermediates: used as a source of piperidine ring in the synthesis of a few insecticides or fungicides.
2. Coordination chemistry: forms complexes with metal ions for catalysis or material modification.

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