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Isonipecotic Acid

Product name Isonipecotic Acid,
Piperidine-4-carboxylic acid,
4-Piperidinecarboxylic acid
CAS No. 498-94-2
Molecular formula C6H11NO2
Use

Drug intermediates:
1. Used for synthesizing analgesics (such as fentanyl derivatives) and local anesthetics (such as piperidinecarboxylate compounds).
2. Construct the pyridine ring structure of antipsychotic drugs (such as certain dopamine receptor modulators).
3. Participate in the preparation of antihistamines or anticholinergic drugs (such as some drugs used to treat Parkinson's disease).

Anti cancer research:
1. As a fragment for synthesizing targeted anticancer drugs (such as kinase inhibitors), enhancing cell penetration by modifying the pyridine ring.

Organic synthesis:
1. Chiral synthesis: Piperidine rings can serve as chiral adjuvants or ligands (such as in asymmetric catalytic reactions).
2. Multi functional group construction: Carboxyl groups can be further derived into esters, amides, or acyl chlorides, expanding molecular diversity.

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